Quantification Strategies for Two-Dimensional Liquid Chromatography Datasets Using Regions of Interest and Multivariate Curve Resolution Approaches

Quantification of identical and unique segments in ethylene-propylene copolymers using two dimensional liquid chromatography with infra-red detection

Hyphenating High Temperature High Performance Liquid Chromatography (HT-HPLC) with High Temperature Size Exclusion Chromatography (HT-SEC) (High Temperature Two Dimensional Liquid Chromatography (HT-HPLC x HT-SEC or HT 2D-LC)) leads to an isocratic elution in the second dimension, which in turn enables to use IR detector (quantitative detection) for monitoring the eluting polymers. Experimental...

Correspondence Quantification in Comprehensive Two-Dimensional Liquid Chromatography

This correspondence corrects the description in a recent paper by Mondello et al., “Quantification in Comprehensive Two-Dimensional Liquid Chromatography” [Mondello, L.; Herrero, M.; Kumm, T.; Dugo, P.; Cortes, H.; Dugo, G. Anal. Chem., 2008, 80, 5418-5424], of previous research on peak integration. This correspondence also shows that the peak integration method proposed in that paper is equiva...

Determination of phenolic acids in strawberry samples by means of fast liquid chromatography and multivariate curve resolution methods.

Use of Multivariate Curve Resolution Alternating Least Squares (MCR-ALS) is evaluated in the analysis of nine phenolic acids, both in standards mixture samples and in strawberry juice samples, by liquid chromatography with diode array detection (LC-DAD). Chromatographic coelution problems either because of unknown matrix interferences or because of the increase of organic modifier to reduce chr...

High-resolution separation of cardiovascular proteomes: two-dimensional electrophoresis and liquid chromatography.

Quantification of tamoxifen in pharmaceutical formulations using micellar liquid chromatography.

This paper describes a micellar liquid chromatographic method used to analyze tamoxifen (TAMO) in pharmaceutical formulations, while focusing in its interesting features. Solid samples were solved in a micellar solution, irradiated at 254 nm, filtered and injected. Extraction steps were avoided and thus expediting the procedure. Tamoxifen was resolved in <5 min, using a mobile phase containing ...